PLA2G2D in tumour-draining lymph nodes regulates anti-tumour immunity
Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10954-1
A specific population of macrophages that express high levels of the enzyme PLA2G2D in tumour-draining lymph nodes is associated with poor prognosis in patients, and inhibiting PLA2G2D improves anti-tumour immunity in mouse models.
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